It's hard to discuss Coquimbo without also talking about nearby La Serena. The seaport city of Coquimbo certainly has impressive sights of its own, like the beautiful mosque with colorful interior details, the 300-foot brutalist Cruz del Tercer Milenio, which offers incredible views… and yes, even the local fish market! But over in nearby La Serena — which is actually a popular vacation destination for Chileans — you'll find great reasons to make the side-trip: restored buildings from the Spanish colonial period, a 19th-century cathedral, the local archaeological museum and more. Plus, you won't want to miss Chile's famous local wines, harvested nearby in the region's Elqui Valley.